A new study has found that sarcolipin, which is a small protein only found in muscles, can help increase energy expenditure of the muscles and fat oxidation when responding to exercise or cold. “This study shows a direct relationship between sarcolipin and energy metabolism. This mechanism is intrinsic to muscle and generates heat at the expense of fat burning,” says Muthu Periasamy, senior author of the paper and professor at Sanford Burnham Prebys Medical Discovery Institute (SBP), Lake Nona.
“When we feed mice with more sarcolipin a high-fat diet, they don’t accumulate any fat in their muscle, and they don’t develop insulin resistance and type 2 diabetes,” says Santosh Maurya, first author of the paper. “Researchers have already shown that extreme obesity reduces sarcolipin function. There might be a therapeutic window to increase sarcolipin recruitment to burn more energy. This strategy could help people with metabolic conditions, as well as those who have difficulty exercising,” said Periasamy.
We wonder if this protein is the answer to all our fat related problems. Stay tuned for more updates.